← Back to The Cognitive Edge Compound Overview P21, also referred to in the literature as P021, is a tetrapeptide derived from a specific region of the ciliary neurotrophic factor (CNTF) sequence. CNTF is a full-length protein that belongs to the cytokine superfamily and has documented interactions with neurotrophin signaling infrastructure. The peptide fragment that […]

← Back to The Cognitive Edge Compound Overview: Research Context Only GHK-Cu is a copper-binding tripeptide, glycyl-L-histidyl-L-lysine, identified in biological matrices across research contexts. Its affinity for copper ions is what gives it biochemical relevance. The copper chelation is not incidental. It appears central to how the compound interacts with cellular signaling machinery. GHK-Cu is […]

← Back to The Cognitive Edge Dihexa is a synthetic peptidomimetic, meaning it is a small molecule engineered to mimic certain structural features of a peptide without being a full peptide chain. It was developed as a derivative of Nle1-angiotensin IV, itself an analog of angiotensin IV, a short signaling peptide most people associate with […]

← Back to The Cognitive Edge Research Overview Dihexa is a synthetic peptide that has attracted attention in neuroscience research circles over the past decade, primarily because of its proposed ability to amplify a signaling pathway that most researchers do not immediately associate with synaptogenesis. The compound is derived from angiotensin IV, but its mechanism […]

← Back to The Cognitive Edge Research Overview Semax is a synthetic peptide originally derived from the ACTH(4-7) fragment of adrenocorticotropic hormone, a naturally occurring brain signaling molecule. It has been studied in Russian pharmacological research for decades, and over the past few years, Western research groups have started paying closer attention to it. What […]

Mechanisms Being Explored in Selank Research

← Back to The Cognitive Edge Research Context Selank is a synthetic heptapeptide, meaning it is a chain of seven amino acids assembled in a laboratory setting. Its structural origin is tuftsin, an endogenous tetrapeptide with known immunomodulatory properties, carrying the sequence Thr-Lys-Pro-Arg. Selank extends this base sequence by appending Pro-Gly-Pro to the C-terminal end, […]